ATP5S
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| ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B) | |||||||||||
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| Identifiers | |||||||||||
| Symbols | ATP5S; ATPW; HSU79253 | ||||||||||
| External IDs | MGI: 1915305 HomoloGene: 12232 GeneCards: ATP5S Gene | ||||||||||
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| Orthologs | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | 27109 | 68055 | |||||||||
| Ensembl | ENSG00000125375 | ENSMUSG00000054894 | |||||||||
| UniProt | Q99766 | Q9CRA7 | |||||||||
| RefSeq (mRNA) | NM_001003803 | NM_026536 | |||||||||
| RefSeq (protein) | NP_001003803 | NP_080812 | |||||||||
| Location (UCSC) | Chr 14: 49.85 - 49.87 Mb | Chr 12: 70.64 - 70.66 Mb | |||||||||
| PubMed search | [1] | [2] | |||||||||
ATP synthase subunit s, mitochondrial is an enzyme that in humans is encoded by the ATP5S gene.[1][2][3]
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified.[3]
References
- ^ Belogrudov GI, Hatefi Y (Feb 2002). [Expression error: Missing operand for > "Factor B and the mitochondrial ATP synthase complex"]. J Biol Chem 277 (8): 6097-103. doi:. PMID 11744738.
- ^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). [Expression error: Missing operand for > "A "double adaptor" method for improved shotgun library construction"]. Anal Biochem 236 (1): 107-13. doi:. PMID 8619474.
- ^ a b "Entrez Gene: ATP5S ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27109.
Further reading
- Kinosita K, Yasuda R, Noji H (2003). [Expression error: Missing operand for > "F1-ATPase: a highly efficient rotary ATP machine."]. Essays Biochem. 35: 3–18. PMID 12471886.
- Oster G, Wang H (2003). [Expression error: Missing operand for > "Rotary protein motors."]. Trends Cell Biol. 13 (3): 114–21. doi:. PMID 12628343.
- Leyva JA, Bianchet MA, Amzel LM (2003). [Expression error: Missing operand for > "Understanding ATP synthesis: structure and mechanism of the F1-ATPase (Review)."]. Mol. Membr. Biol. 20 (1): 27–33. doi:. PMID 12745923.
- Sanadi DR, Pringle M, Kantham L, et al. (1984). [Expression error: Missing operand for > "Evidence for the involvement of coupling factor B in the H+ channel of the mitochondrial H+-ATPase."]. Proc. Natl. Acad. Sci. U.S.A. 81 (5): 1371–4. doi:. PMID 6143319.
- Yu W, Andersson B, Worley KC, et al. (1997). [Expression error: Missing operand for > "Large-scale concatenation cDNA sequencing."]. Genome Res. 7 (4): 353–8. PMID 9110174.
- Elston T, Wang H, Oster G (1998). [Expression error: Missing operand for > "Energy transduction in ATP synthase."]. Nature 391 (6666): 510–3. doi:. PMID 9461222.
- Wang H, Oster G (1998). [Expression error: Missing operand for > "Energy transduction in the F1 motor of ATP synthase."]. Nature 396 (6708): 279–82. doi:. PMID 9834036.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). [Expression error: Missing operand for > "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."]. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
- Cross RL (2004). [Expression error: Missing operand for > "Molecular motors: turning the ATP motor."]. Nature 427 (6973): 407–8. doi:. PMID 14749816.
- Ma J, Dempsey AA, Stamatiou D, et al. (2007). [Expression error: Missing operand for > "Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects."]. Atherosclerosis 191 (1): 63–72. doi:. PMID 16806233.
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