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alemán árabe búlgaro checo chino coreano croata danés eslovaco esloveno español estonio farsi finlandés francés griego hebreo hindù húngaro indonesio inglés islandés italiano japonés letón lituano malgache neerlandés noruego polaco portugués rumano ruso serbio sueco tailandès turco vietnamita

definición - HOXC13

definición de HOXC13 (Wikipedia)

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HOXC13

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Homeobox C13
Identifiers
SymbolsHOXC13; HOX3; HOX3G
External IDsOMIM142976 MGI99560 HomoloGene7770 GeneCards: HOXC13 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez322915422
EnsemblENSG00000123364ENSMUSG00000001655
UniProtP31276P50207
RefSeq (mRNA)NM_017410NM_010464
RefSeq (protein)NP_059106NP_034594
Location (UCSC)Chr 12:
52.62 - 52.63 Mb
Chr 15:
102.75 - 102.76 Mb
PubMed search[1][2]

Homeobox protein Hox-C13 is a protein that in humans is encoded by the HOXC13 gene.[1][2][3]

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla.[3]

Contents

See also

References

  1. ^ McAlpine PJ, Shows TB (Aug 1990). [Expression error: Missing operand for > "Nomenclature for human homeobox genes"]. Genomics 7 (3): 460. PMID 1973146. 
  2. ^ Scott MP (Dec 1992). [Expression error: Missing operand for > "Vertebrate homeobox gene nomenclature"]. Cell 71 (4): 551-3. PMID 1358459. 
  3. ^ a b "Entrez Gene: HOXC13 homeobox C13". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3229. 

Further reading

  • Godwin AR, Capecchi MR (2000). [Expression error: Missing operand for > "Hair defects in Hoxc13 mutant mice."]. J. Investig. Dermatol. Symp. Proc. 4 (3): 244–7. doi:10.1038/sj.jidsp.5640221. PMID 10674376. 
  • Panagopoulos I, Isaksson M, Billström R, et al. (2003). [Expression error: Missing operand for > "Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13)."]. Genes Chromosomes Cancer 36 (1): 107–12. doi:10.1002/gcc.10139. PMID 12461755. 
  • Acampora D, D'Esposito M, Faiella A, et al. (1990). [Expression error: Missing operand for > "The human HOX gene family."]. Nucleic Acids Res. 17 (24): 10385–402. doi:10.1093/nar/17.24.10385. PMID 2574852. 
  • Rabin M, Ferguson-Smith A, Hart CP, Ruddle FH (1987). [Expression error: Missing operand for > "Cognate homeo-box loci mapped on homologous human and mouse chromosomes."]. Proc. Natl. Acad. Sci. U.S.A. 83 (23): 9104–8. doi:10.1073/pnas.83.23.9104. PMID 2878432. 
  • Apiou F, Flagiello D, Cillo C, et al. (1996). [Expression error: Missing operand for > "Fine mapping of human HOX gene clusters."]. Cytogenet. Cell Genet. 73 (1-2): 114–5. doi:10.1159/000134320. PMID 8646877. 
  • Flagiello D, Gibaud A, Dutrillaux B, et al. (1997). [Expression error: Missing operand for > "Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines."]. FEBS Lett. 415 (3): 263–7. doi:10.1016/S0014-5793(97)01118-6. PMID 9357979. 
  • de Stanchina E, Gabellini D, Norio P, et al. (2000). [Expression error: Missing operand for > "Selection of homeotic proteins for binding to a human DNA replication origin."]. J. Mol. Biol. 299 (3): 667–80. doi:10.1006/jmbi.2000.3782. PMID 10835276. 
  • Kulessa H, Turk G, Hogan BL (2001). [Expression error: Missing operand for > "Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle."]. Embo J. 19 (24): 6664–74. doi:10.1093/emboj/19.24.6664. PMID 11118201. 
  • Kosaki K, Kosaki R, Suzuki T, et al. (2002). [Expression error: Missing operand for > "Complete mutation analysis panel of the 39 human HOX genes."]. Teratology 65 (2): 50–62. doi:10.1002/tera.10009. PMID 11857506. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). [Expression error: Missing operand for > "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."]. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). [Expression error: Missing operand for > "Complete sequencing and characterization of 21,243 full-length human cDNAs."]. Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Pruett ND, Tkatchenko TV, Jave-Suarez L, et al. (2005). [Expression error: Missing operand for > "Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13."]. J. Biol. Chem. 279 (49): 51524–33. doi:10.1074/jbc.M404331200. PMID 15385554. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). [Expression error: Missing operand for > "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."]. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

 

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