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definiciones
Thecoma (n.)
1.(MeSH)A gonadal stromal neoplasm composed only of THECA CELLS, occurring mostly in the postmenopausal OVARY. It is filled with lipid-containing spindle cells and produces ESTROGENS that can lead to ENDOMETRIAL HYPERPLASIA; UTERINE HEMORRHAGE; or other malignancies in postmenopausal women and sexual precocity in girls. When tumors containing theca cells also contain FIBROBLASTS, they are identified as thecoma-fibroma tumors with less active hormone production.
sinónimos
diccionario analógico
Ovarian Diseases - Cancer of Endocrine Gland, Cancer of the Endocrine Gland, Carcinoma of Endocrine Gland, Endocrine Cancer, Endocrine Gland Cancer, Endocrine Gland Carcinoma, Endocrine Gland Neoplasms, Neoplasms, Endocrine Gland - Female Genital Neoplasms, Genital Neoplasms, Female - Gonadal Tissue Neoplasms, Neoplasms, Gonadal Tissue[Hyper.]
Cancer of Ovary, Cancer of the Ovary, Neoplasms, Ovarian, Ovarian Cancer, Ovarian Neoplasms, Ovary Cancer, Ovary Neoplasms - Gynandroblastoma, Sex Cord-Gonadal Stromal Tumors, Sex Cord-Stromal Tumor[Hyper.]
Thecoma (n.)
[MeSH]
Wikipedia
Thecoma
| Thecoma | |
|---|---|
| Classification and external resources | |
 High magnification micrograph of a thecoma. H&E stain. |
|
| ICD-9 | 220 |
| ICD-O: | 8600 |
| MeSH | D013798 |
Thecomas or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified as sex cord-stromal tumours.
They are typically estrogen-producing and they occur in older women (mean age 59; 84% after menopause). (They can, however, appear before menopause.[1])
Sixty percent of patients present with abnormal uterine bleeding, and 20% have endometrial carcinoma.
Pathologic features
Low magnification micrograph of a thecoma showing compression of the ovarian cortex (right of image). H&E stain.
Grossly, the tumour is solid and yellow.
Grossly and microscopically, it compress of the ovarian cortex.
Microscopically, the tumour cells have abundant lipid-filled cytoplasm.
References
- ^ Okada I, Nakagawa S, Takemura Y, et al. (October 2004). "Ovarian thecoma associated in the first trimester of pregnancy". J. Obstet. Gynaecol. Res. 30 (5): 368–71. DOI:10.1111/j.1447-0756.2004.00212.x. PMID 15327450. http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1341-8076&date=2004&volume=30&issue=5&spage=368.
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